白莉，女，博士，国家食品安全风险评估中心，研究员/微生物实验室主任，现为中华预防医学会食品卫生分会主任委员，FAO/WHO微生物风险评估专家委员会委员（JEMRA），WHO食源性疾病负担流行病学专家组成员（FERG），国家食品安全风险评估专家委员会委员和食品安全国家标准审评委员会委员，获中共北京市委组织部北京市优秀人才青年拔尖个人。主要从事食品微生物检验工作体系建设和方法学研究，重点开展食源性致病菌分子流行病学、耐药性传播及疾病负担研究。作为第一负责人，承担十三五、十四五科技部重大研发课题、国家自然科学基金面上项目及北京市对外合作交流项目等多个项目，承担国家标准制修订2 项。以通讯作者或第一作者发表SCI论文40 余篇，中英文专著5部。兼任SCI杂志Foodborne Pathogens and Disease和中文杂志《微生物学报》的编委及China CDC weekly 青年编委。作为国务院联防联控机制综合组工作组成员先后参与广州等8地疫情应急处置工作。

研究方向：

1.食品微生物检验工作体系建设和方法学研究；

2.全国食品安全风险监测网耐药监测及重要耐药致病菌的风险评估；

3.我国特有重要耐药食源性致病菌的流行特征及归因分析。

主要承担的课题和标准：

（一）省部级科研课题

1. 主持，国家重点研发计划，畜禽重要耐药病原菌/耐药基因的传播风险评估，350万，在研。

2. 主持，国家重点研发计划，新发和重大食源性疾病标准化诊断、调查及处置技术体系研究，350万，结题。

3. 主持，首发科技专项，基于多准则决策分析和人工神经网络的食源性疾病负担分级分类技术体系研究，100万，在研。

4. 主持，国家外专局项目，食品生产链条中重要耐药病原菌及其耐药机制的流行、传播和人群健康风险及控制研究，20万，在研。

5. 主持，国家自然科学基金委面上项目，ST17型印第安纳沙门菌高水平耐药形成发展的分子机制和微进化研究，60万，已结题。

6. 子课题负责人，国家自然科学基金国际合作项目，中土两国食品生产链中替加环素耐药菌的流行特征和基因组特征研究，15万，在研。

7.子课题负责人，国家自然科学基金重点项目，可移动tet(X)变异体介导替加环素高水平耐药的产生与传播机制，58万，在研。

8. 子课题负责人，北京市科委项目，肉制品中食源性致病菌对消毒剂耐受的评价规范研究，25万，结题。

（二）食品安全国家标准

1. 主持，食品安全国家标准 产志贺毒素大肠埃希氏菌检验，15万，结题。

2. 主持，食品安全国家标准 食品微生物学检验 阪崎肠杆菌检验 GB5009.40-2016，15万，结题。

近期发表的代表性论文：

（一）发表论文

1. Xiaoyu Lu, Pei Zhang, Pengcheng Du, Xiuli Zhang, Juan Wang, Yingying yang, Honghu Sun, Zhiqiang Wang, Shenghui Cui, Ruichao Li, Li Bai*.Prevalence and Genomic Characteristics of mcrPositive Escherichia coli Strains Isolated from Humans, Pigs, and Foods in China. Microbiology Spectrum, 2023 (online 12th April), ISSN 2165-0497. DOI: 10.1128/spectrum.04569-22

2. Mengdi Yuan, Rongwei Han, Li Bai*, Yinping Dong, Qian Xi, Qijing Du, Yongxin Yang, Fereidoun Forghani, Qingli Yang, Juhee Ahn & Jun Wang*. Recent Advances in the Characterization of Burkholderia Gladioli Pv. Cocovenenans and Its Toxin Production. Food Reviews International, 2023 (online), ISSN 8755-9129. DOI:10.1080/87559129.2023.2199829.

3. Ning Li, Li Bai*. Comparative study on foodborne bacterial antimicrobial resistance surveillance system in China, America and Europe and Its implication. Journal of Food Science and Technology, Volume 41, Issue 1, 2023, Pages 1-9. ISSN 2095-6002. DOI:10.12301/spxb202200918.

4. Yujiao Mu, Ruichao Li, Pengcheng Du, Pei Zhang, Yan Li, Shenghui Cui, Séamus Fanning, Li Bai*. Genomic Epidemiology of ST34 Monophasic Salmonella enterica Serovar Typhimurium from Clinical Patients from 2008 to 2017 in Henan, China. Engineering,Volume 15, 2022, 34-44. ISSN 2095-8099. DOI:10.1016/j.eng.2022.05.006

5. Li Bai, Jun Wang, Lisha Liu, Shenghui Cui, Yunchang Guo, Ning Li, Zhaoping Liu. Implications for risk management of foodborne pathogens in China from the outbreak of monophasic salmonella enterica serovar Typhimurium contaminated chocolate products. Chinese Journal of Preventive Medicine, Volume 56, Issue 11, Nov 2022, Pages 1648-1656. ISSN 0253-9624. DOI: 10.3760/cma. j.cn112150-20220712-00711.

6. Li Bai, Lisha Liu, Liangliang Li, Yeru Wang, Yibaina Wang, Yan Qi, Ping Fu, Zhaoping Liu, Yunchang Guo, Ning Li. Comparison of foodborne disease outbreaks data in China and the United States from 2011 to 2017 and its inspiration for the construction of monitoring system in China. Chinese Journal of Food Hygiene. Volume 34, Issue 5, 2022, Pages 863-870. ISSN 1004-8456. DOI:10.13590/j.cjfh.2022.05.001.

7. Mi Lu, Weishuai Zhai, Pengcheng Du, Yang Wang, Zhifei Zhan, Shuai Chen, Huayun Jia, Li Bai*. Molecular characteristics of ciprofloxacin‑cefotaxime‑azithromycin co‑resistant Salmonella enterica Serovar Thompson in foodborne diseases in Hunan Province. Chinese Journal of Preventive Medicine, Volume 56, Issue 12, Dec 2022, Pages 1745-1750. ISSN 0253-9624. DOI: 10.3760/cma.j.cn112150-20220112-00046.

8. Huanjing Sheng, Jiaqi Ma, Qiuping Yang, Wei Li, Qian Zhang, Chengqian Feng, Jin Chen, Mingqian Qin, Xiumin Su, Puyao Wang, Jie Zhang, Wei Zhou, Linna Zhao, Li Bai*, Shenghui Cui*, Baowei Yang*. Prevalence and characteristics of mcr-9-positive Salmonella isolated from retail food in China. Lebensmittel-Wissenschaft und-Technologie, Volume 160, Issue 3, Feb 2022, 113261, ISSN 0023-6438. DOI:10.1016/j.lwt.2022.113261.

9. Zhanqiang Su, Ling Zhang, Honghu Sun, Ying Hu, Séamus Fanning, Pengcheng Du, Shenghui Cui, Li Bai*. Characterization of Non-O157 Shiga Toxin-Producing Escherichia coli Cultured from Cattle Farms in Xinjiang Uygur Autonomous Region, China, During 2016–2017. Foodborne Pathogens and Disease, Volume 18, Issue 11, Nov 2021, Pages 761-770, ISSN 1535-3141. DOI: 10.1089/fpd.2020.2843.

10. Honghu Sun, Weishuai Zhai, Yulin Fu, Ruichao Li, Pengcheng Du, Li Bai*. Co-occurrence of plasmid-mediated resistance genes tet(X4) and blaNDM-5 in a multidrug-resistant Escherichia coli isolate recovered from chicken in China. Journal of Global Antimicrobial Resistance, Volume 24, Mar 2021, Pages 415-417, ISSN 2213-7165. DOI: 10.1016/j.jgar.2021.02.010.

11. Pengcheng Du, Pei Zhang, Juan Wang, Ruichao Li, Séamus Fanning, Li Bai*. Molecular characterization of two novel NDM-1-producing atypical enteroaggregative Escherichia coli isolates from patients. Plasmid, Volume 115, May 2021, 102568, ISSN 0147-619X. DOI: 10.1016/j.plasmid.2021.102568.

12. Ruichao Li, Pengcheng Du, Pei Zhang, Yan Li, Xiaorong Yang, Zhiqiang Wang, Juan Wang, Li Bai*. Comprehensive Genomic Investigation of Coevolution of mcr genes in Escherichia coli Strains via Nanopore Sequencing. Global Challenges, Volume 5, Issue 3, Jan 2021, 2000014, ISSN 2056-6646. DOI: 10.1002/gch2.202000014.

13. Li Bai, Yeru Wang, Yibaina Wang, Yongning Wu, Ning Li, Zhaoping Liu. Controlling COVID-19 Transmission due to Contaminated Imported Frozen Food and Food Packaging. China CDC Weekly, Volume 3, Issue 2, Mar 2021, Pages 30-33, ISSN 2096-7071. DOI: 10.46234/ccdcw2021.008.

14. Xianying Zeng, Suling Lv, Cong Qu, Lan Lan, Dongmei Tan, Xiugui Li, Li Bai*. Serotypes, antibiotic resistance, and molecular characterization of non-typhoidal salmonella isolated from diarrheic patients in Guangxi Zhuang Autonomous Region, China, 2014–2017, Food Control, Volume 120, 2021, 107478, ISSN 0956-7135. DOI:10.1016/j.foodcont.2020.107478

15. Honghu Sun, Yuping Wan, Pengcheng Du, Dejun Liu, Ruichao Li, Pei Zhang, Yongning Wu, Séamus Fanning, Yang Wang, Li Bai*. Investigation of tigecycline resistant Escherichia coli from raw meat reveals potential transmission among food-producing animals. Food Control, Volume 121, 2021, 107633, ISSN 0956-7135. DOI:10.1016/j.foodcont.2020.107633

16. Li Bai, Yeru Wang, Yibaina Wang, Yan Qi, Zhaoping Liu, Xinan Jiao. Progress and challenge of food microbiological risk assessment in China. Chinese Journal of Food Hygiene. Volume 32, Issue 6, 2020, Pages 598-603. ISSN 1004-8456. DOI:10.13590/j.cjfh.2020.06.002.

17. Huayun Jia, Qingli Dong, Ge Zhao, Li Bai*. Progress and challenge of food microbiological risk assessment in China. Chinese Journal of Food Hygiene. Volume 32, Issue 5, 2020, Pages 576-581. ISSN 1004-8456. DOI:10.13590/j.cjfh.2020.05.020.

18. Pengcheng Du, Dejun Liu, Huangwei Song, Pei Zhang, Ruichao Li, Yulin Fu, Xiao Liu, Jinli Jia, Xiaodi Li, Séamus Fanning, Yang Wang, Li Bai*, Hui Zeng. Novel IS26-mediated hybrid plasmid harbouring tet(X4) in Escherichia coli. Journal of Global Antimicrobial Resistance, Volume 21, 2020, Pages 162-168, ISSN 2213-7165. DOI: 10.1016/j.jgar.2020.03.018.

19. Huayun Jia, Qingli Dong, Ge Zhao, Bai Li*. Research progress in quantitative risk assessment of non-typhoid salmonella in pork and its products. Chinese Journal of Food Hygiene. 2020,32(05):576- 581.

20. Bai Li. The progress of the expert group meeting of the Food and Agriculture Organization of the United Nations/World Health Organization on the control measures of Shiga toxin-producing Escherichia coli in the production and processing of beef and raw milk products. Chinese Journal of Food Hygiene, 2020, 32(05):589- 591.

21. Li Bai, Yeru Wang, Yibaina Wang, Qan qi, Zhaoping Liu, Xinan Jiao. Progress and Challenges of Food Microbiological Risk Assessment in China. Chinese Journal of Food Hygiene, 2020, 32(05):589- 591.

22. Pei Zhang, Juan Wang, Xinglong Wang, Xue Bai, Jiangang Ma, Ruyi Dang, Yifei Xiong, Séamus Fanning, Li Bai* and Zengqi Yang*. Characterization of Five Escherichia coli Isolates Co-expressing ESBL and MCR-1 Resistance Mechanisms from Different Origins in China. Frontiers in Microbiology, 2019, 10. DOI: 10.3389/fmicb.2019.01994.

23. Honghu Sun, Yuping Wan, Pengcheng Du, Li Bai*. The Epidemiology of Monophasic Salmonella Typhimurium. Foodborne Pathogens and Disease,2019. DOI: 17. 10.1089/fpd.2019.2676.

24. Li Bai, Pengcheng Du, Yinju Du, Honghu Sun, Pei Zhang, Yuping Wan, Qi Lin, Séamus Fanning, Shenghui Cui, Yongning Wu*. Detection of plasmid-mediated tigecycline-resistant gene tet(X4) in Escherichia coli from pork, Sichuan and Shandong Provinces, China, February 2019. Euro Surveill. 2019;24(25):pii=1900340. DOI:10.2807/1560-7917.ES.2019.24.25.1900340.

25. Li Bai, Mingjing Xu, Weiwei Li, Haihong Han, Jikai Liu, Ping Fu, Lizi Xu, Yingying Ouyang, Xinyong You, Jiang Chen, Jing Zou, Yue Dai, Shiqi Zhen, Shenggang Duan, Junhua Liang, Yunchang Guo. Retrospective case analysis of crayfish-transmitted Haff disease in China during 2016-2017. Food Control, 2019, 104:181-186.

26. Ruichao Li, Pei Zhang, Xiaorong Yang, Zhiqiang Wang, Séamus Fanning, Juan Wang, Pengcheng Du, Li Bai*. Identification of a hybrid plasmid coproducing MCR-1 and novel MCR-3 variant from an Escherichia coli strain. J Antimicrob Chemother, 2019, 74(6):1517-1520. DOI:10.1093/jac/dkz058.

27. Li Bai, Jikai Liu, Weiwei Li, Ping Fu, Ning Li, Xiumei Liu, Yunchang Guo. Comparison of foodborne disease surveillance systems in China and the U. S. Capital Journal of Public Health. 2018,12(02):62-67.DOI:10.16760/j.cnki.sdggws.2018.02.002.

（二）获奖情况

中国新发食源性病原菌艾伯特埃希菌的分离和特征研究，2021年，四川省科学技术奖，三等奖，四川省人民政府。

（三）论著

1.肉类预制调理食品，中国农业科学技术出版社，2023，北京，主编.

2.产志贺毒素大肠埃希菌（STEC）和食物：归因、特征和监测，中国原子能出版社，2021，北京，主译.

3.产志贺毒素大肠埃希菌导致疾病的食物归因，中国原子能出版社，2021，北京，主译.

4.中国食源性沙门氏菌耐药现状和趋势分析，中国质检出版社，2017，北京，副主编.

（四）专利

全基因组测序数据的分析方法和装置，第二发明人. 专利号：ZL 2023 10523080.8，2023年。

联系方式：

地址：北京市朝阳区潘家园南里7号

电话：010-67768526

邮箱：baili@cfsa.net.cn